Antivirals – COVID

Angie Szumlinski News

In a recent press release, Merck (NYSE: MRK), announced preliminary results of viral RNA (molnupiravir), an investigational oral antiviral agent, from a Phase 2a randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability, and efficacy to eliminate SARS-CoV-2. The study showed a reduction in time (days) to negativity of infectious virus isolation in nasopharyngeal swabs from participants with symptomatic SARS-CoV-2 infection.

Of 202 treated participants, no safety signals have been identified and of the four serious adverse events reported, none were considered to be study drug related. In addition to the ongoing clinical studies, Merck has conducted a comprehensive, non-clinical program to characterize the safety profile of molnupiravir. “We are very pleased to share our initial Phase 2 infectivity data at this important conference, which remains at the forefront for critical clinical scientific information in infectious diseases” shared Dr. Wendy Painter, Chief Medical Officer of Ridgeback Biotherapeutics. “At a time where there is unmet need for antiviral treatments against SARS-CoV-2, we are encouraged by these preliminary data.”

“We continue to make progress in our Phase 2/3 clinical programs evaluating molnupiravir in both outpatient and hospital settings and plan to provide updates when appropriate” said Dr. Roy Baynes, senior vice president and head of global clinical development, chief medical officer, Merck Research Laboratories. What a breath of fresh air! Take that COVID-19!

Stay the course, stay well, mask up, get vaccinated, and stay tuned!