Hydroxychloroquine – Does it Work?

Angie SzumlinskiHealth, Studies

That is the big question. There are researchers who believe it does and there are researchers who say it doesn’t. Hard to know who to believe right? In a multicentered, blind, placebo-controlled, randomized trial conducted at 34 hospitals in the U.S., adults hospitalized with respiratory symptoms from severe acute respiratory syndrome coronavirus 2 infections were enrolled between April 2 and June 19, 2020. Patients were randomly assigned to hydroxychloroquine (400 mg twice daily for 2 doses, then 200 mg twice daily for 8 doses).

Among 479 patients who were randomized:

  • Median age, 57 years,
  • 20.1% in the intensive care unit,
  • 46.8% receiving supplemental oxygen without positive pressure,
  • 11.5% receiving non-invasive ventilation or nasal high-flow oxygen and
  • 6.7% receiving invasive mechanical ventilation or extracorporeal membrane oxygenation.

Among adults hospitalized with respiratory illness from COVID-19, treatment with hydroxychloroquine, compared with placebo, did not significantly improve clinical status at day 14. These findings do not support the use of hydroxychloroquine for the treatment of COVID-19 among hospitalized adults. Again, there are other studies that differ, but the bottom line is, a vaccine is on the horizon and it can’t be available soon enough! Stay the course, stay strong, stay well, mask up, and stay tuned!