Non-Steroidals and COVID-19

Angie Szumlinski Studies

“Non-steroidal anti-inflammatory drugs (NSAIDs) provide effective analgesia and are important in the treatment of inflammatory diseases. In March, 2020, the French health ministry and media discussed unpublished data showing that use of NSAIDs could increase the severity of COVID-19. More recent studies have found no association between NSAID use, admission to hospital, and worse outcomes for patients with COVID-19.

Studies of patients with non-SARS-CoV-2 respiratory infection have found associations between NSAID (including cyclooxygenase (COX)-2 inhibitors) use and increased rates of complications. These studies found that NSAID use was associated with higher rates of myocardial infarction, pleural empyema, and longer length of hospital stay. However, outcomes used in such pneumonia studies… are less frequent in patients with SARS-CoV-2 infection.”

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study” – Thomas M Drake, MBChB et al. May 7, 2021

Bottom line, we appreciate the research, and need to stay informed and follow the advice of our primary care provider. There is no crystal ball; we are all following expert guidance and hopefully as things “calm down” we will enjoy the benefits of patience and research!

Stay well, mask up indoors, and stay tuned!