NSAIDs or Acetaminophen

Angie Szumlinski
|
February 23, 2021
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More people with fever and body aches are turning to non-steroidal anti-inflammatory drugs (NSAIDs) to ease symptoms, but the drugs have come under new scrutiny as investigators work to determine whether they are a safe way to relieve the pain of COVID-19 vaccination or symptoms of the disease. One theory is that NSAIDs alter susceptibility to infection by modifying angiotensin-converting enzyme 2 (ACE2). The drugs might also change the cell entry receptor for SARS-CoV-2, alter virus replication, or even modify the immune response.

NSAIDs work by inhibiting cyclooxygenase (COX)-1 and COX-2 enzymes in the body, which are crucial for the generation of prostaglandins. These lipid molecules play a role in inflammation and are blocked by NSAIDs. Lots of big words, confusing?

Bottom-line, get vaccinated when you are able, check with your physician before taking any medications, including over-the-counter medications pre and post vaccine. Stay the course, stay well, get vaccinated, mask up and stay tuned!


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